Keywords: natural product, pharmacognosy, phytochemistry, phytoanalysis, chromatography Internship Duration: 01/01/22 - 30/06/22
Head of the hosting team: Prof. Judit Homann DSc.
Website: Click here
Address of the host laboratory: Research group 1 Team Phytochemistry research group Eötvös u. 6. 6720 Szeged Hungary
Supervisor 1: Dr. Andrea Vasas Ph.D. dr. habilE-mail: vasas@pharmacognosy.hu Phone: +3662546451
Supervisor 2: Dr. Dora Redei Ph.D.E-mail: redei@pharmacognosy.huPhone: +3662546451
Chemical identification of plant metabolites, isolation of compounds from plant extracts, characterization of the composition of plant extracts, essential oil analysis.
Instruments for phytoanalytical and preparative phytochemical work: LC-MS (API 2000), HPLC with PDA, UV and RI detectors (Waters, Shimadzu, Jasco Able); SCF-HPLC (Jasco); Chromatotron centrifugal chromatograph (Harrison Research); counter-current partition chromatograph (Armen CPC Spot); MPLC device (Büchi); gas chromatographs with MS and FID detectors (Shimadzu, HP 5890 Series 2); CombiFlash; TLC-UV/VIS densitometer; UV spectrophotometers; Hettich centrifuge; permanent access to spectrometers: NMR 500 MHz, 600 MHz, Bruker; Q-Exactive Orbitrap UPLC with mass spectrometer
1. Lajter I, Vasas A, Beni Z, Forgo P, Binder M, Bochkov V, Zupko I, Krupitza G, Frisch R, Kopp B, Hohmann J Sesquiterpenes from Neurolaena lobata and their antiproliferative and anti-inflammatory activities. Journal of Natural Products 77:(3) pp 576–582. (2014), 10.1021/np400834c. 2. Kúsz N, Orvos P, Bereczki L, Fertey P, Bombicz P, Csorba A, Tálosi L, Jakab G, Hohmann J, Rédei D Diterpenoids from Euphorbia dulcis with potassium ion channel inhibitory activity with selective g protein-activated inwardly rectifying ion channel (GIRK) blocking effect Journal of Natural Products 81:(11) pp 2483-2492. (2018), 10.1021/acs.jnatprod.8b00500.
