Internship for EUGLOH program

Keywords: protein delivery, nanoparticles, solid dosage forms

Internship Duration: 01/01/22 - 30/06/22

During the internship the formulation of protein loaded nanoparticles would be offered, with a possibility of full characterization with FT-IR, Raman, TG-DSC, XRPD, particle size, zeta potential measurement methods, followed by formulation into various solid dosage forms (films, tablets, pellets), the details may bdiscussed upon the request of the candidates

The research group deals with the design and testing of solid dosage forms, tablets, granules, capsules, polymer films. We have tablet machines equipped with a force measure cell, granulators equipped with temperature and humidity sensors, coating apparatus and devices for pharmacopoeial and analytical investigations of solid dosage forms. We also have the ability to perform analytical studies, thermoanalytical studies (DSC, TG), FTIR, XRPD and RAMAN mapping, SEM, contact angle and surface free energy (SFE) measurement, tensile strength (hardness) of films, in vitro mucoadhesion test, etc.

1. Ibrahim Y, Regdon Jr. G, Kristó K, Kelemen A, Adam M E, Hamedelniel E I, Sovány T, Design and characterization of chitosan/citrate films as carrier for oral macromolecule delivery, European Journal of Pharmaceutical Sciences, 2020 (146) 105270
2. Ranjous Y, Regdon Jr. G, Pintye-Hódi K, Varga T, Szenti I, Kónya Z, Sovány T, Optimization of the production process and product quality of titanate nanotube–drug composites, Nanomaterials 9 (2019) 1406 doi: 10.3390/nano9101406 8
3. Ranjous Y, Regdon Jr. G, Pintye-Hódi K, Sovány T, Standpoint on the priority of TNTs and CNTs as targeted drug delivery systems, Drug Discovery Today 24 (2019) 1704-1709 doi: 10.1016/j.drudis.2019.05.019 9.

• Medicine and health sciences, Veterinary science
• Pharmacy, Biology, Physics and Chemistry