EUGLOH logo

BA/BsC, MA/MSc, PhD Internship for EUGLOH program

Title: Reproducibility of muscular oxygenation & effects of Blood Flow Restriction pressure level on cardiovascular responses

Keywords: Cardiovascular adaptation, Blood Flow Restriction, Sport, Performance, NIRS

Internship Duration: 07/02/22 - 01/07/22


Head of the hosting team: Michel-Ange AMORIM

Website: Click here

Address of the host laboratory:
Laboratoire Complexité, Innovation, Activités Motrices et Sportives (CIAMS)
Team Equipe Mouvement Humain , Adaptation et Performance Sportive (M.H.A.P.S)
Faculté des Sciences du Sport, Université Paris-Saclay, Bât. 335 rue Pierre de Coubertin
91405 Orsay cedex I France

Supervisor 1: Marie GERNIGON
E-mail: marie.gernigon@universite-paris-saclay.fr
Phone: 0169158111

Supervisor 2: Julien DESANLIS
E-mail: julien.desanlis@universite-paris-saclay.fr


Internship description:

Abstract:
Blood Flow Restriction (BFR) training method involves decreasing blood flow to a muscle by application of an external constriction device, such as a blood pressure cuff, to provide mechanical compression of the underlying vasculature (Slysz et al., 2016). While some studies have used absolute occlusion pressures (Abe et al., 2010), it is now recommended to use personalised occlusion pressure (McEwen et al., 2019) based on determination of chosen limb arterial occlusion pressure (AOP) (Loenneke et al., 2012). However, a wide range of occlusion pressures are reported to be used in the literature. It is recommended to choose a BFR pressure between 40-80% of AOP (Patterson et al., 2019). The aim of this mechanical compression is to restrict the venous return to the heart, which limits re-oxygenation. Muscular oxygenation measured by near-infrared spectroscopy (NIRS) seems reproducible at rest after muscle ischaemia (McManus et al., 2018) but shows higher within-subject variability at exercise (Thiel et al., 2011) without BFR. Moreover, several studies have investigated the effects of BFR pressure levels on cardiovascular kinetics, particularly on the upper limb, showing that higher pressures induce higher HR or and lower tissue saturation index (TSI%), while others not (Wei et al., 2021). Most of the studies cited previously focused on small muscle mass, but recent findings of Wei et al. (2021) show similar cardiovascular responses for tested BFR pressures (40%, 50%, 60%, 70%, 80% of AOP) during constant load cycling.
Thus, the aim of this study is to investigate the reproducibility of muscular oxygenation and to evaluate the amplitude of cardiovascular responses to different BFR pressure levels during a cycling task.

Supervisors:
Marie GERNIGON: marie.gernigon@universite-paris-saclay.fr
François COTTIN: francois.cottin@universite-paris-saclay.fr
Julien DESANLIS: julien.desanlis@universite-paris-saclay.fr

Techniques used during the internship:

Partial Blood Flow Restriction
Heart rate variability (HRV)
Muscular Near InfraRed Spectrometry (NIRS)

Bibliography:

Abe, T., Fujita, S., Nakajima, T., Sakamaki, M., Ozaki, H., Ogasawara, R., Sugaya, M., Kudo, M., Kurano, M., Yasuda, T., Sato, Y., Ohshima, H.-S., Mukai, C., & Ishii, N. (2010). Effects of low-intensity cycle training with restricted leg blood flow on thigh muscle volume and VO2max in young men. Journal of Sports Science and Medicine, 9(3), 452–458. http://www.jssm.org
Loenneke, J. P., Fahs, C. A., Rossow, L. M., Sherk, V. D., Thiebaud, R. S., Abe, T., Bemben, D. A., & Bemben, M. G. (2012). Effects of cuff width on arterial occlusion: implications for blood flow restricted exercise. European Journal of Applied Physiology, 112(8), 2903–2912. https://doi.org/10.1007/s00421-011-2266


Possibility of PhD : No decided yet

Research field(s) of interest to the hosting team:
Language(s) spoken in the host laboratory: French and English