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MA/MSc Internship for EUGLOH program

Title: Multi-objective optimization and deep learning for healthcare applications

Keywords: Deep learning, Multi-objective optimization, Transformers, EHR

Internship Duration: 30/11/-1 - 30/11/-1


Head of the hosting team: Feng Chu

Website: Click here

Address of the host laboratory:
IBISC
Team AROB@S
23, Boulevard de France
91034 Evry France

Supervisor 1: Farida ZEHRAOUI
E-mail: farida.zehraoui@univ-evry.fr
Phone: +33164853464

Supervisor 2: Eric Angel
E-mail: eric.angel@univ-evry.fr


Internship description:

Stochastic gradient descent methods are widely used in machine learning, particularly to optimize the parameters of deep neural networks (deep learning).
Most gradient descent methods aim to optimize a single function representing a single objective or a linear combination of multiple objectives. Recently, variants of gradient descent for multiobjective optimization have been proposed in the literature [1]. These methods have been used for multi-task learning [2].
We developed, in the AROB@S team, a multi-objective approach that aims to optimize the architecture of a neural network by removing neurons and connections between neurons during the learning phase to improve efficiency and model interpretability. This internship aims to adapt this approach to multi-task learning using real data from electronic health records of patients admitted to intensive care units (MIMIC-IV) [4]. Hypernetworks [5] or multi-objective gradient descent [2] will be used for multi-objective optimization.

Techniques used during the internship:

- Study of the multi-objective approach proposed in our team as well as state-of-the-art deep learning architectures based on attention mechanisms like Transformers [3].
- Adapt and implement the proposed approach to process time series and generate a Pareto front.
- Apply the implementation to real-world time series data of patients while considering multiple tasks,
including early predictions of sepsis.

Bibliography:

[1] S. Liu, L.N. Vicente, The stochastic multi-gradient algorithm for multi-objective optimization and its application to supervised machine learning, arXiv:1907.04472, 2021.
[2] Sener, O., & Koltun, V. Multi-task learning as multi-objective optimization. NeurIPS, 2018.
[3] Rasmy, L., Xiang, Y., Xie, Z., Tao, C., & Zhi, D. (2021). Med-BERT: pretrained contextualized embeddings on large- scale structured electronic health records for disease prediction. NPJ digital medicine, 4(1), 1-13.
[4] Johnson, A.E.W., Bulgarelli, L., Shen, L. et al. MIMIC-IV, a freely accessible electronic health record dataset. Sci Data 10, 1 (2023). https://doi.org/10.1038/s41597-022-01899-x
[5] Navon, Aviv & Shamsian


Possibility of PhD : Yes

Research field(s) of interest to the hosting team:
Language(s) spoken in the host laboratory: French, english